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Image 1/1 : Lovo, one of the study villages in the rural health zone of Kimpese, Bas-Congo Province, DRC

PhD defence Joule Madinga Ntwan

Epidemiology of polyparasitism with schistosomes, Taenia solium and soil-transmitted helminths in co-endemic settings of the Democratic Republic of Congo

19 janv. 2018

Supervisors

  • Prof. dr. Katja Polman (ITM)
  • Prof. dr. Niko Speybroeck (UCL)
  • Prof. dr. Pascal Lutumba (DR Congo)

Summary

This thesis presents results of parasitological studies conducted in rural areas of DRC. Our findings indicate that single and co-infections with soil-transmitted helminths, schistosomes and taeniasis/cysticercosis are common and are heterogeneously distributed in space and within host populations. Co-endemicity of these helminth infections, similarities in age profiles and existence of shared risk factors between single and co-infections are suggestive of an integrated control approach. However, the use of praziquantel in an area potentially endemic for neurocysticercosis calls for caution given the risk of severe neurological side effects. This thesis also shows that mixed Schistosoma infections can alter the efficacy of praziquantel treatment, though this effect disappears after cumulative treatments. The findings of this thesis may contribute to the improvement of prevention and control of polyparasitism in DRC and elsewhere.

Please confirm your attendance by sending an email to jmadinga@yahoo.fr