INTRODUCTION
PREFACE
Introductory Remarks :
C.E.Gordon Smith
SECTION I. EBOLA VIRUS INFECTION
1. CLINICAL ASPECTS
Clinical Aspects of Ebola Virus Infection in Yambuku Area, Zaire, 1976
P.Piot, P.Sureau, J.G.Breman, D.L.Heymann, V.Kintoki, N.Masamba, M.Mbuyi, M.Miatudila, J.F.Ruppol , S.van Nieuwenhove, H.K.White, G.van der Groen, P.A.Webb, H.Wulff and K.M.Johnson
Clinical Aspects of Ebola Virus Disease at the Ngaliema Hospital, Kinshasa, Zaire, 1976
M.Isaacson, P.Sureau, G.Courteille and S.R.Pattyn
African Haemorrhagic Fever in the Southern Sudan, 1976 : The Clinical Manifestations
D.H.Smith, D.P.Francis and D.I.H.Simpson
Isolation, Monitoring and Treatment of a Case of Ebola Virus Infection
R.T.D.Emond
Discussion
2. PATHOLOGY, VIRUS MORPHOLOGY, TAXONOMY
Human Pathology of Ebola (Maridi) Virus Infection in the Sudan
H.H.Schumacher, D.Peters and J.Knobloch
Pathology of Ebola Virus Infection
F.A.Murphy
Ebola and Marburg Virus Morphology and Taxonomy
F,A.Murphy, G.van der Groen, S.G.Whitfield and J.V.Lange
Discussion
3. LABORATORY DIAGNOSIS
Virological Diagnosis of Ebola Virus Infection
S.R.Pattyn
Observations on the Properties of Ebola Virus
A.Webb, K.M.Johnson, H.Wulff and J.V.Lange
Virological Studies on a Case of Ebola Virus Infection in Ilan and in Monkeys
E.T.W.Bowen, G.Lloyd, G.S.Platt, L.B.McArdell, P.A.Webb and D.I.H.Simpson
Discussion
4. EPIDEMIOLOGY
The Epidemiology of Ebola Haemorrhagic Fever in Zaire, 1976
J.G.Breman, P.Piot, K.M.Johnson, M.K.White, M.Mbuyi, P.Sureau, D.L.Heymann, S.van Nieuwenhove, J.B.McCormick, J.P.Ruppol, V.Kintoki, M.Isaacson, G.van der Groen, P.A.Webb and K.Ngvete
Discussion
The Haemorrhagic Fever Outbreak in Maridi, Western Equatoria, Southern Sudan
Babiker El Tahir
Ebola Fever in the Sudan, 1976 : Epidemiological Aspects of the Disease
D.P.Francis, D.H.Smith, R.B.Highton, D.I.H.Simpson, Pacifico Lolik, Isiaih Mayom Deng, Anthony Lagu Gillo, Ali Ahmed Idris and Babiker El Tahir
The Nzara Outbreak of Viral Haemorrhagic Fever
D.H.Smith, D.P.Francis, D.I.H.Simpson and R.B.Highton
Viral Haemorrhagic Fever in the Sudan, 1976 : Human Virological and Serological Studies
E.T.W.Bowen, G.S.Platt, G.Lloyd, L.B.McArdle, D.I.H.Simpson, D.H.Smith, D.P. Francis, R.B.Highton, M.Cornet, C.C.Draper, Babiker El Tahir, Isiaih Mayon Deng, Pacifico Lolik and Oliver Duku
DiscussionContainment and Surveillance of an Epidemic of Ebola Virus Infection
in Yambuku Area, Zaire, 1976
P.Sureau, P.Piot, J.G.Breman, J.F.Ruppol, M.Masamba, H.Berquist, D.L.Heymann, V.Kintoki, M.Koth, M.Mandiangu, H.Mbuyi, T.Muyembe, M.Miatudila, J.B.McCormick, M.Ngoy, G.Raffier, N.Sambu, M.K.White, S.van Nieuwenhove and M.Zayembwa
Containment and Surveillance of a Hospital Outbreak of Ebola Virus Disease
in Kinshasa, Zaire, 1976
M.Isaacson, J.F.Ruppol, R.Collas, N.Matundu, Tshibariba and K.Omombo
DiscussionContainment and Surveillance of the Ebola Virus Epidemic in Southern Sudan
Pacifico Lolik
Collection of Mammals and Arthropods during the Epidemic of Haemorrhagic Fever in Zaire
M.Germain
Approaches towards Studies on Potential Reservoirs of Viral Haemorrhagic Fever
in Southern Sudan (1977)
A.A.Arata and B.Johnson
Results of Ebola Antibody Surveys in Various Population Groups
G.van der Groen, K.M.Johnson, P.A.Webb, H.Wulff and J.V.Lange
Logistics in Epidemiological Investigations
C.C.Draper
Discussion5. PLASMAPHERESIS PROGRAMS
Plasmapherese dans le Foyer Epidemique de Yambuku, Zaire
D.Courtois, N.Isaacson et B.Dujeu
Plasmapheresis Measures in Sudan
D.I.H.Simpson, J.Knobloch, C.C.Draper and J.Blagdon
Evaluation of the Plasmapheresis Program in Zaire
K.H.Johnson, P.A.Webb and D.L.Heymann
Discussion6. PROBLEMS AND FUTURE NEEDS
Disseminated Intravascular Coagulation
M.Verstraete
Discussion
The Development of a Vaccine against African Hemorrhagic Fever
G.A.Eddy and F.E.Cole jr
DiscussionThe Effect of Interferon on Experimental Ebola Virus Infection in Rhesus Monkeys
E.T.W. Bowen, A. Baskerville, K. Cantell, G.F. Mann, D.I.H. Simpson and A.J. Zuckerman
DiscussionGrowth of Lassa and Ebola Viruses in Different Cell Lines
G.van der Groen, P.A.Webb, K.M.Johnson, J.V.Lange, H.Lindsay and L.Eliott
Attempts to Classify Ungrouped Arboviruses by Electron Microscopy
A.El Mekki, G.van der Groen and S.R.Pattyn
DiscussionSECTION II. OTHER HAEMORRHAGIC FEVERS
Marburg Virus Disease
M.Dietrich
DiscussionLassa Fever : Historical Review and Contemporary Investigation
J.B.McCormick and K.M.Johnson
DiscussionLassa Fever Virus Antibodies in Mastomys Natalensis caught in Different Parts of Nigeria
A.Fabiyi, B.Dobrokhotov, O.Tomori and A.A.Arata
DiscussionSouth American Haemorrhagic Fevers
L.Valverde Chinel
Crimean-Congo Hemorrhagic Fever
J.Casals
DiscussionRickettsioses : Current Problems of Clinical Interest
Th.E.Woodward
DiscussionKorean Hemorrhagic Fever
Ho Wang Lee
Nephropathia Epidemica
C.-H.von Bonsdorff, M.Brummer-Korvenkontio, T.Hovi, J.Lähdevirta, N.Oker-Blom, K.Penttinen, P.Saikku and A.Vaheri
SECTION III. PUBLIC HEALTH ASPECTS
1. SURVEILLANCE IN ENDEMIC COUNTRIES
Ebola Haemorrhagic Fever : A Public Health Problem
P.Brès
Surveillance of Haemorrhagic Fever in Endemic Areas : Sudan
A.A.Idris and K.S.Daoud
Surveillance of Haemorrhagic Fever in Endemic Areas : Kenya
D.H.Smith
The Surveillance of Viral Haemorrhagic Fever in Zaire
L.Muyembe Tamfum
2. LABORATORY AND FIELD EQUIPMENT
Laboratory and Field Safety Equipment for the Manipulation of Highly Infectious Agents
K.M.Johnson
Discussion3. HOSPITALISATION
Hospitalisation of Patients Suspected of Highly Infectious Disease
R.T.D.Emond
DiscussionThe Planning of a Modern Isolation Unit in the Netherlands
H.Bijkerk
4. TRANSPORT AND INTERNATIONAL SURVEILLANCE
Ebola Virus Disease (EVD) Surveillance and Medical Evacuation of International Medical Commission Members in Zaire
M.Isaäcson, O.W.Prozesky, K.M.Johnson, S.O.Foster and D.Courtois
International Surveillance and Transport of Ebola Virus Disease and Other Haemorrhagic Fevers : the UK Experience
L.M.Roots
Surveillance and Transport of Patients with Suspect Viral Hemorrhagic Fevers : the United States Experience
J.A.Bryan and R.M.Zweighaft
Discussion
PARTICIPANTS
AUTHOR INDEX