Prince Leopold Institute of Tropical Medicine

MIDDLE AND NEAR EAST

 

PREVENTION OF MALARIA  |   DIARRHOEA  |   VACCINATIONS

 

 

       

 

 

 

MIDDLE AND NEAR EAST

There is no malaria in BAHRAIN, the UNITED ARAB EMIRATES, ISRAEL, JORDAN, KUWAIT, LEBANON or QATAR. The malaria risk in OMAN and SYRIA is limited to a few remote areas; hence no prophylactic antimalaria tablets are necessary for these countries.

AFGHANISTAN: There is malaria in all areas of Afghanistan below 2000 m, from May to November (the majority of cases are caused by the benign vivax-malaria, but there is also some malaria falciparum). There is no risk of malaria in the Central and Eastern part of the country, which lies above 2000 metres. There is no prominent risk of malaria in the capital Kabul. The recommendations for prevention of malaria discussed in NOTE 2 are applicable for stays in high risk rural areas.

IRAQ: There is only a malaria risk (exclusively due to the mild vivax-malaria) from May to November in areas of the provinces north of 35 degrees latitude north (Duhok, Erbil, Sulaimaniya) that are below 1500 m. There is also a risk in a few remote places in the province of Basra in the extreme south, near the border with Iran. For stays in a risk area, in the countryside, see the recommendations for malaria prevention described in NOTE 1.

IRAN: There is only a (limited) malaria risk :

  • during summer (from May to November) in the provinces Ardebil and East Azerbijan (in the far north, north of the Zagros mountain chain) (only benign vivax malaria): see NOTE 1.

  • from March to November in various remote rural areas of some southeastern provinces (tropical region of Iran), i.e. the provinces Hormozgan, the tropical region of Kerman and the Southern part of Sistan and Baluchestan. Chloroquine-resistant malaria falciparum is possible. See NOTE 2.
     

OMAN: Very limited risk in a few remote areas (in the province of Musandam, the extreme tip of the peninsula in the North of the country). No cases have been reported since 2003. No chemoprophylaxis is necessary.

PAKISTAN: There is no risk of malaria in areas higher than 2000 m (mainly the high mountains in the far North of the country), nor in the centers of large cities. The recommendations for prevention of malaria discussed in NOTE 2 apply in the rest of the country.

SAUDI ARABIA: The risk of malaria (especially P. falciparum) is restricted to the southwest coast in the Western Province "South Western region" (including the border with Yemen and the coastal area around the Red Sea). There is no risk in the towns of Jeddah, Mecca, Taif and Medina. There is no risk of malaria in the other provinces (Eastern, Northern and Central Provinces), nor in the highlands of the Asir Province. The recommendations for prevention of malaria discussed in NOTE 2 apply for trekking trips in the rural areas.

SYRIA: There is a only a very limited risk of malaria, focal in a number of rural areas in the El Hasaka Governorate in the northeastern border area with Iraq (no malaria cases have been reported since 2005), and only from May to October (exclusively due to benign vivax malaria). There is no malaria risk in the rest of the country. The standard precautions against mosquito bites in the evening and at night are sufficient. No preventive measures against malaria are necessary according to the World Health Organisation.

TURKEY: There is no risk of malaria in most parts of Turkey. There is a small risk – exclusively of the benign vivax type - from May to October in rural areas restricted to a narrow strip in the South of Turkey, on the border with Syria (South Anatolia): the region around the coastal town of Mersin, the area around Adana, Çukurova/Amikova up to the Iraqi border. The recommendations for prevention of malaria discussed in NOTE 1 apply here for a trekking trip in the rural regions.

YEMEN: There is no risk of malaria in the capital San’a. In the rest of the country there is a limited risk from March to August. Precautions should therefore be taken to protect yourself against mosquito bites in the evenings and at night. Between September and February recommendations for prevention of malaria outlined in NOTE 2 apply for stays in primitive conditions. There is only a limited risk on Socotra Island (from March to August), precautions against mosquito bites in the evening and at night are sufficient. In case of fever after a stay in Yemen, malaria should always be considered.

 

 

 

 

 

 

PREVENTION OF MALARIA

Precautions against mosquito bites in the evenings and at night are always essential to protect against malaria. People visiting a malaria area during the daytime and staying in good hotels in the evenings and overnight run no risk, and do not need to take antimalaria tablets. They should always have a mosquito-repellent to be applied to their skin at hand just in case they are unable to get back to the hotel on time in the evening, for example because of problems such as illness, car breakdown, etc. You should also generously apply mosquito-repellent to the skin when travelling in the early morning, in the evening or at night. Those taking an outdoor trip (especially to rural areas) and spending the night in primitive conditions are advised to impregnate the mosquito net with permethrine or deltamethrine, a chemical substance that provides an extra mosquito-repellent and mosquitocidal effect; antimalaria tablets are also necessary.
N.B. In many Asian regions (http://www.dtg.org/21.0.html) one can dispense with the chemoprophylaxis (also for adventurous travellers) after having had an extensive talk with a specialized doctor who will evaluate the malaria risk depending on the type of lodging and only when strict measures are taken against mosquito bites from dusk till dawn and malaria emergency treatment is available (Malarone®) with complete instructions.
 

NOTE 1

NIVAQUINE® 3 tablets per week, taken all in one dose, starting from 1 week before departure, and continuing until 4 weeks after returning home.

NOTE 2

MALARONE® (1 tablet daily from 1 day before departure until 7 days after returning home) OR DOXYCYCLINE (1 tablet daily from 1 day before departure until 4 weeks after return; in some cases it is better to start the medication a few days in advance to check the tolerance) OR LARIAM® (1 tablet once a week from 2-3 weeks before departure until 4 weeks after returning home) are the first-choice antimalaria drugs.
In order to have an effective level of LARIAM® in the blood, it is best to start taking the medication 2 to 3 weeks before departure. People who have never taken this medication before should start 2 to 3 weeks beforehand in order to deal with possible side effects (e.g. dizziness, insomnia, nightmares, agitation, inexplicable anxiety, cardiac palpitations). Lariam will not be prescribed if the doctor considers that there are contra indications (women trying to get pregnant, epilepsy, depression, or cardiac rhythm disorders for which certain medications such as beta-blockers, calcium antagonists or digitalis are taken) or unless Lariam was not tolerated on an earlier occasion. The medication should be continued for 4 weeks after returning home. If Lariam® is well tolerated, it can if necessary be taken for many months and even years.
For short trips MALARONE is generally well tolerated and is an excellent but expensive alternative. It can also be taken for several months, but is in that case an expensive choice.
DOXYCYCLINE (100 mg per day, starting the day before departure until 4 weeks after returning home or after leaving risk area).  Doxycycline must be taken while sitting down, with plenty of liquid or during a meal. It can sometimes give rise to phototoxicity and fungal infections of the mouth or genitals. Doxycycline can be taken for several months.
All this should be individually discussed with your doctor or with the doctor at a travel advice centre.

 

 

 

DIARRHOEA

DIARRHOEA is a frequent problem when travelling. Even when travelling in good conditions, it is not always possible to avoid it. Some advice and the correct medications from the travel pharmacy are very useful.
Be sure to consult the information on travellers’ diarrhoea where preventive measures and the correct treatment of diarrhoea are discussed.

 

       
 

 

 

 

DENGUE

In the Middle and Near East dengue fever may occur. Prevention = apply protective measures against mosquito bites during the day. Consult the text on dengue: www.travelhealth.be & consult the world card www.who.int/ith ® "disease distribution maps".

 

   

 

 

 

 

 

VACCINATIONS

  • No vaccinations are required.

  • YELLOW FEVER vaccination is NOT required if you are departing from Belgium. There is no risk of yellow fever. If you are travelling from another country where yellow fever can occur (Africa, South America, see http://www.who.int/ith/en/index.html ® disease distribution maps), you should be vaccinated from the age of 1 year, for Afghanistan, Bahrain, Iraq, Jordan, Oman, Saudi Arabia and Syria, and for Pakistan and Lebanon from the age of 6 months.

  • Going on a trip is also an ideal opportunity for bringing TETANUS, DIPHTHERIA, PERTUSSIS, MEASLES and POLIOMYELITIS VACCINATIONS up to date.

  • Anyone travelling to Asia, regardless the duration and conditions of the trip, should be vaccinated against HEPATITIS A. If you are staying in poor hygienic conditions, go abroad frequently or for a long time (e.g. for at least 2-3 weeks), vaccination against TYPHOID is also recommended.
    In many cases, vaccination against HEPATITIS B should also be considered. For further information, please consult the general information on VACCINATIONS.

  • In specific circumstances, travellers should consider having a vaccination against RABIES. Pilgrims to Mecca are obliged to have a vaccination against MENINGOCOCCUS ACWY MENINGITIS.
    All t
    his should be individually discussed with your doctor or with the doctor at the travel advice centre.