Prince Leopold Institute of Tropical Medicine

INDIA - SRI LANKA - MALDIVES - NEPAL - BANGLADESH - BHUTAN - MYANMAR (BURMA)

 

MALARIA PREVENTION  |   DIARRHOEA  |   VACCINATIONS

 

 

 

 

 

 

 

SOUTH ASIA

INDIA:

In India there is risk of malaria infection (also on the Andaman and Nicobar islands), but this varies greatly according to the area and the season; there can also be strong annual variations. However it is impossible to specify the place and/or season of the states and the regions with an actual risk in the Indian subcontinent, because there are no reliant data available.

We state the following:
· For travellers spending the night in very good conditions (luxury hotels) the precautions on mosquito bites in the evening and at night are sufficient.

· All other travellers (backpackers, travellers on the night train or hiker via hostels and lodges,..), should follow the recommendations discussed in NOTE 1.

 

Map: malaria in India: http://www.itg.be/ITG/Uploads/MedServ/India2010.pdf

 

No risk > 2000 m
1. Jammu & Kashmir
2. Sikkim
3. Himachal Pradesh
B variable limited risk (Note 1)
4. Punjab
5. Haryana
6. Uttaranchal
7. Rajasthan
8. Uttar Pradesh
9. Bihar
10. Andhra Pradesh
11. Kerla
12. Tamilnadu
C variable elevated risk (Note 1)
13. Gujarat                     23. Arunachal Pradesh
14. Madhya Pradesh   24. Assam
15. Chhatisgarh           25. Nagaland
16. Jharkhand              26. Manipur
17. Orissa                     27. Tripura
18. Maharashtra           28. Mizoram
19. Goa                          29.  Andaman & Nicobar
20. Karnataka
21. Bengale
22. Meghalaya

 
  1. There is no malaria risk in the mountainous areas (above 2000 m) of the northern provinces Kashmir, Jammu, Sikkim and Himachal Pradesh. No preventive measures are therefore necessary there.

  2. The risk of malaria is low to non-existent in the large town centres and is on average somewhat lower in the southern tip of the Indian continent, namely south of the line connecting Madras, Bangalore and Mangalore. The measures discussed in NOTE 1 apply for travellers staying their nights in primitive conditions. (Malarone, Lariam).

  3. The risk of falciparum malaria and drug resistance are relatively higher in the north-eastern states (in the Assam region between Bangladesh, China and Myanmar), on the Andaman and Nicobar Islands, and in the states Chhattisgarh, Goa, Gujarat, Jharkhand, Karnataka (with exception of the city of Bangalore), Madhya Pradesh, Maharashtra (with exception of the cities of Mumbai, Nagpur, Nasik and Pune), Orissa and West Bengal (with exception of the city of Kolkata). The measures discussed in NOTE 1 apply here. (Malarone, doxycycline, Lariam).

          http://www.searo.who.int/EN/Section10/Section21/Section340_4015.htm ® India
 

 

SRI LANKA: There is no malaria risk in Colombo, Galle, Gampaha (North of Colombo), the Kalutara & Matara districts (South of Colombo), nor in the central district of Nuwara Eliya (http://www.malariajournal.com/content/2/1/22/ Figures 1 & 2). Measures for protection against mosquito bites in the evenings and at night are sufficient here. In case of fever, malaria should always be considered.

However, in the rest of the country below 800 m, which is most areas, there is a variable but relatively low malaria risk, and the protective measures against mosquito bites in the evenings and at night are sufficient for travellers who spend the nights in very good conditions (exclusively luxury hotels); however, the recommendations for prevention of malaria discussed in NOTE 1 apply for other travellers. In case of fever, malaria should always be considered.

http://www.searo.who.int/EN/Section10/Section21/Section340_4015.htm ® Sri Lanka


MALDIVES: There is no malaria risk.

http://www.searo.who.int/EN/Section10/Section21/Section340_4015.htm ® Maldives

NEPAL: There is only risk of malaria (mainly vivax malaria) in a number of rural Terai areas. These are the southern provinces in the narrow border strip with India, lying below 1200 metres. Occasionally epidemics of Plasmodium falciparum malaria still occur between July and October. The risk of vivax malaria is seasonal. There is no risk of malaria in the rest of Nepal, or in the capital Kathmandu. The recommendations for prevention of malaria discussed in NOTE 1 apply for travellers spending the night in primitive conditions in the malaria risk regions in the Teraļ, especially in the border areas with India.

http://www.searo.who.int/EN/Section10/Section21/Section340_4015.htm ® Nepal


BANGLADESH: There is a risk of malaria. In the large towns (such as Dakka, the capital, and Chittagong) the risk is non-existent or extremely low, and the precautions against mosquito bites in the evenings and at night are sufficient. In case of fever, malaria should always be considered.
The risk is very high in the "Chittagong Hill Tract districts", the border districts in the north and east along the border with the Assam region of India and the border with Myanmar (Burma), especially in the forested regions and in the foothills of the mountains (mainly in Sylhet, Moulavibazar, Habiganj, Sunaganj, Netrokona, Mymensingh, Sherpur, Kurigram, Cox’s Bazar, Bandarban, Rangamati, Chittagong, Khagrachar). The recommendations for prevention of malaria discussed in NOTE 1 apply here. (Serious resistance to Nivaquine has been reported).
In the rest of Bangladesh (outside the capital Dhakka, and the border provinces) there is a varying malaria risk. Travellers who spend the night in very good conditions (exclusively luxury hotels) can follow the recommendations against mosquito bites in the evening and at night. In case of fever, malaria should always be considered. Other travellers in these regions should follow the instructions of NOTE 1

http://www.searo.who.int/EN/Section10/Section21/Section340_4015.htm ® Bangladesh


BHUTAN: There is no malaria in areas above 1700 metres, or in the capital Thimbu. There is some risk of malaria in the rural areas of five southern districts (Chhukha, Samchi, Samdrup Jongkhar,
Geylegphug and Shemgang) bordering on India, below 1700 m, where the recommendations as discussed in NOTE 1 apply.

http://www.searo.who.int/EN/Section10/Section21/Section340_4015.htm ® Bhutan


MYANMAR (Burma): There is no risk of malaria in the cities of Yangon (Rangoon) and Mandalay. There is a varying risk of malaria in areas

below 1000 m.
· The protective measures against mosquito bites in the evening and at night are sufficient for travellers who spend the night in the large resorts in very good conditions (only luxury hotels). In case of fever, malaria should always be considered.
· Additional protective measures depending on the risk area are indicated for other travellers:

a)      The whole year in the Karen State (Kayin), on the border with Thailand (see NOTE 2)

b)      Seasonal risk:

-        From March to December in the eastern states of Kachin, Kayah and Shan; the measures discussed in NOTE 2 apply;  in the other states of Chin, Mmon, Rakhine, the provinces of Pegu, Hlegu and Hmawbi and the Taikkyi municipal districts of the Yangon Province (formerly Rangoon); the measures discussed in NOTE 1 apply.

-         From April to December in the rural areas of the Tenasserim province (NOTE 1).

-         From May to December in Irrawaddy Div. and the rural areas of the Mandalay province. In these frequently visited areas of the central plateau between Mandalay and Yangon (Rangoon), which are irrigated by the Irrawady river, the malaria risk is very low, especially on the eastern side. Mosquito protection measures are sufficient when staying in good conditions.

-         From June to November in the rural areas of the Magwe and Sagaing Provinces. (NOTE 1).

There is important Lariam resistance in the eastern half of the country, therefore Malarone® or Doxycycline is recommended (CDC 2010).

http://www.searo.who.int/EN/Section10/Section21/Section340_4015.htm ® Myanmar

 

 

 

 

 

 

MALARIA PREVENTION

Protective measures against mosquito bites in the evening and at night are always essential for protection against malaria. Individuals who visit a malaria area during the daytime and stay in a good hotel in the evening run no risk and do not need to take any antimalaria tablets. A mosquito repellent (for application to the skin) should always be carried, in case returning to the hotel in time in the evening proves impossible i.e. due to problems such as illness, car breakdown, etc. The mosquito repellent should also be generously applied to the skin when going on a trip in the early morning, in the evening or at night. On outdoor trips to the countryside with an overnight stay in primitive conditions it is certainly advisable to impregnate the mosquito net with permethrine or deltamethrine, a chemical substance that produces an extra mosquito-repellent and mosquitocidal effect. Taking antimalaria tablets is also necessary.
N.B. In many Asian regions (http://www.dtg.org/21.0.html
) one can dispense with the chemoprophylaxis (even for adventurous travellers) after having had an extensive talk with a specialized doctor who will evaluate the malaria risk depending on the type of accomodation and only if strict measures are taken against mosquito bites from dusk till dawn and emergency malaria treatment is available (Malarone®) with complete instructions.

NOTE 1

MALARONE® (1 tablet daily from 1 day before departure until 7 days after returning home) OR DOXYCYCLINE (1 tablet daily from 1 day before departure until 4 weeks after returning home; in some cases a tolerance test during a few days is necessary) OR LARIAM® (1 tablet once a week, from 2-3 weeks before departure until 4 weeks after returning home)  are the first-choice antimalaria drugs.
In order to have an effective level of LARIAM® in the blood upon arrival, it is best to start taking the medication 2 to 3 weeks before departure. People who have never taken this medication before should start 2 to 3 weeks beforehand in order to deal with possible side effects (e.g. dizziness, insomnia, nightmares, agitation, inexplicable anxiety, cardiac palpitations). Lariam will not be prescribed if the doctor considers that there are contra indications (women trying to get pregnant, epilepsy, depression, or cardiac rhythm disorders for which certain medications such as beta-blockers, calcium antagonists or digitalis are taken) or unless Lariam was not tolerated on an earlier occasion. The medication should be continued for 4 weeks after returning home. If Lariam® is well tolerated, it can if necessary be taken for many months and even years. For short trips MALARONE is generally well tolerated and is an excellent but expensive alternative. It can also be taken for several months.
DOXYCYCLINE: (100 mg daily, starting the day before departure, and continuing until 4 weeks after returning home). Doxycycline must be taken while sitting down with plenty of liquid or during a meal. Doxycycline can sometimes give rise to phototoxicity and fungal infections of the mouth or genitals. Doxycycline can be taken for several months.
All this should be discussed with your doctor or with the doctor at the travel advice centre.

NOTE 2

MALARONE® (1 tablet daily from one day before departure until 7 days after return) OR DOXYCYCLINE (100 mg daily, starting the day before departure, and continuing until 4 weeks after returning home. Doxycycline must be taken while sitting down with plenty of liquid or during a meal. Doxycycline can sometimes give rise to phototoxicity and fungal infections of the mouth or genitals. Doxycycline can be taken for several months).
This should be discussed with your doctor or with the doctor at the specialist travel advice centre.

 

 

 

DIARRHOEA

DIARRHOEA is a frequent problem when traveling. Even when travelling in good conditions, it is not always possible to avoid it. Advice and the correct medication from the travel pharmacy are very useful.
Please read the information on traveller’s diarrhoea. Preventive measures and correct treatment of diarrhoea are discussed.

 

 
DENGUE


In Asia dengue fever may occur. Prevention = apply protective measures against mosquito bites during the day. Consult the text on dengue on www.travelhealth.be & consult the world card on www.who.int/ith
® "disease distribution maps".
   

 

 

 

 

 

VACCINATIONS

· No vaccinations are required for.
· YELLOW FEVER vaccination is not required if you are departing from Belgium. There is no yellow fever in Belgium. However, if you are travelling from another country where yellow fever can occur (Africa, South America, see http://www.who.int/ith/en/index.html ® disease distribution maps),  you should be vaccinated for India, Sri Lanka, Bangladesh, Nepal, Bhutan, Maldives from the age of 1 year (for India from the age of 6 months).
· Going on a trip is also an ideal opportunity for bringing TETANUS, DIPHTHERIA, PERTUSSIS, POLIOMYELITIS and MEASLES VACCINATIONS up to date.
· Anyone travelling to Asia, regardless of the duration and the circumstances of their stay, should be protected against HEPATITIS A. Vaccination against TYPHOID is in any case advised for people who stay in poor hygienic conditions, or go abroad frequently or for long periods (e.g. for more than 2-3 weeks), even if in good hygienic conditions. In a lot of cases vaccination against HEPATITIS B should also be considered. For more information, please consult the general text on VACCINATIONS.
· People spending more than 4 weeks trekking through the countryside or people who will be staying there for a long time should consider vaccination against JAPANESE ENCEPHALITIS and RABIES.

All this should be individually discussed with your doctor or with the doctor at the travel advice centre.