Prince Leopold Institute of Tropical Medicine

SOUTH AMERICA

 

PREVENTION OF MALARIA  |  DIARRHOEA  |   VACCINATIONS  |   CHAGAS DISEASE

 

 

 

 

 

 

 

SOUTH AMERICA

Maps: http://www.paho.org/English/HCP/HCT/malaria_PPTindex.htm

ARGENTINA: In most of Argentina there is no risk of malaria at all, and therefore no antimalaria precautions are necessary. There is only a limited risk of malaria from October to May in the extreme North of Argentina, only in a few low-lying rural areas (below 1200 metres), and exclusively with the mild vivax form: 1) on the border with Bolivia, in the province of Salta (in the plains of Iruya, Oran, San Martin and Santa Victoria). 2) on the border with Paraguay, in the plains of Misiones and Chaco. The precautions discussed in NOTE 1 apply for travellers spending the night in primitive conditions.

Recommendation of the WHO concerning yellow fever vaccination: "vaccination against yellow fever is strongly recommended for all travellers from the age of 9 months visiting the following areas in Argentina with risk of yellow fever transmission: the northern and north-eastern forested areas of Argentina, including Iguaçu Falls and all areas bordering Brazil and Paraguay, total territory of the federal provinces of Formosa and Misiones, specific areas (departments) of the federal province of Chaco (department of Bermejo), the federal province of Corrientes (departments of Berón de Astrada, Capital, General Alvear, General Paz, Itatí, Ituzaingó, Paso de los Libres, San Cosme, San Miguel, San Martín and San Tomé), the federal province of Jujuy (departments of Ledesma, Santa Bárbara, San Pedro and Valle Grande) and the federal province of Salta (departments of Anta, General José de San Martín, Orán and Rivadavia). This recommendation includes visits to Iguaçu Falls."

BOLIVIA: There is no malaria in the larger towns, nor in the areas above 2500 m. This means that there is no risk in the following high areas in the southwest:

  • in the Oruro province;
  • in a number of provinces in the southwest of the La Paz region, namely in the provinces Ingavi, Los Andes, Omasuyos, Pacajes;
  • in the southern and central part of the Potosi region:

1.       There is Nivaquine-resistant falciparum malaria on the border with Brazil in the Northern provinces Pando and Beni (in a strip of the tropical Amazon basin bordering on the Brazilian states of Acre and Rondonia, especially in Cobija, Guayaramerìn and Riberalta), for which the recommendations discussed in NOTE 2 apply.

2.       There is a limited to very limited malaria risk all year in the areas below 2500 m (but not in the centre of large towns) in the rest of Bolivia (mainly the mild vivax malaria) and anti-mosquito measures are sufficient here. The recommendations discussed in NOTE 1 apply only in the low-lying rural areas of the provinces Santa Cruz (also P. falciparum malaria), Tarija and Chuquisaca on the border with Paraguay and Argentina. In case of fever malaria should always be considered.
Recommendation of the WHO concerning yellow fever vaccination: "vaccination against yellow fever is strongly recommended for travellers visiting the following risk areas; the provinces of Beni, Cochabamba, Santa Cruz and the subtropical part of the province of La Paz. This does not concern the cities of La Paz and Sucre, where there is no risk of yellow fever.
If you are starting your trip from another country where yellow fever can occur (Africa, South America), vaccination is officially required.
http://www.who.int/ith/ITH2010countrylist.pdf

 

BRAZIL: In many areas of Brazil there is no malaria risk at all.

  • There is a possible malaria risk in the forest areas below 900 metres in the 9 states of the "Legal Amazonia Region": Acre, Amapá, Amazonas, Maranhão (only in the West), Mato Grosso (only in the North, not in Mato Grosso do Sul), Pará (except for the city of Belém), Rondônia, Roraima and in Tocantins (in the western part, north of Goias). The measures for the prevention of malaria discussed in NOTE 2 apply only in these areas. There is no risk in the town of Belém (Pará), but a low risk in the urban areas of large towns such as Pôrto Velho (Rondônia), Boa Vista (Roraima), Macapá (Amapà), Manaus (Amazonas), Santarém (Pará), Cuiaba (Mato Grosso), Rio Branco & Cruzeiro do Sul (Acre) and Maraba (Pará). Pantanal National Park is situated in a low risk area, south of Mato Grosso and there is no need to take antimalaria tablets.
  • As stated in the beginning, no precautions against malaria are necessary in the other areas of Brazil. When visiting the Foz de Iguaçu waterfalls, measures for protection against mosquito bites in the evenings and at night will be sufficient.
    Recommendation of the WHO concerning yellow fever vaccination: "Vaccination against yellow fever is strongly recommended for travellers from the age of 9 months visiting the following risk areas; the entire territory of the states of Acre, Amapá, Amazonas, Distrito Federal (also the capital Brasilia), Goiás, Maranh
    ão, Mato Grosso, Mato Grosso do Sul, Minas Gerais, Pará, Rondônia, Roaraima and Tocatins, specific regions of the states: northwest and west Bahia, Espirito Santo, southwest Piaui, central and west Paraná, northwest and central-west Rio Grande do Sul, west Santa Catarina and north and west São Paulo." Vaccination is strongly recommended for travellers visiting Foz de Iguaçu. The complete list with municipalities is available at http://www.saude.gov.br/svs (Febre Amarela). There is no risk of yellow fever in the coastal regions Rio de Janeiro, São Paulo, Salvador, Recife and Fortaleza. If you are starting your trip from another country where yellow fever can occur (Africa, South America), vaccination is officially required from the age of 9 months (except for the travellers for whom the vaccination is medically contra-indicated).

CHILE: No malaria risk.
Recommendation of the WHO concerning yellow fever vaccination: "Vaccination against yellow fever is not obliged nor recommended.

COLOMBIA:

There is no malaria risk in Bogota and its surrounding area, nor in the other large towns. Nor is there any risk in the areas above 800 m on the Cordillera Occidental, Cordillera Central and Cordillera Oriental. There is no risk in most of the Caribbean coastal areas (except in Cordoba) and on the low plains of Colombia, towards the border with Venezuela.
There is a malaria risk which varies greatly from one area to the next all year in many rural areas below 1600 m. The underlined provinces have the highest risk. The recommendations discussed in NOTE 2 apply:

1.       in the Pacific Ocean coastal area – " Pacifico region": in the provinces Nariño, Cauca, Valle del Cauca and Choco

2.       in the Northern region Uraba-Bajo Cauca: provinces Chocó, Antioquia, Córdoba

3.       in the tropical rainforest area of the Amazon basin, the "Amazonian region": provinces Amazonas and Vaupés.

4.       in the remaining regions east of the Andes "orinoquia region": provinces Arauca, Boyaca, Caqueta, Guainía, Guaviare, Meta, Norte de Santander, Putamayo, Vichada.
Recommendation of the WHO concerning yellow fever vaccination: "vaccination against yellow fever is not obliged, but strongly recommended for travellers visiting the following risk areas: middle valley of the Magdalena river, eastern and western foothills of the Cordillera Oriental from the border with Ecuador to that with Venezuela, Urabá, foothills of the Sierra Nevada, eastern plaines (Orinoquia) and Amazonia".
 

ECUADOR:
 

There is no malaria risk above 1500 m, nor in the large towns (such as Quito, Guayaquil and the cities in the Andes region) and on the Galapagos Islands. There is a moderate risk of malaria:

  • in the provinces on the west side of the Andes (Pacific Ocean): Esmeraldas (the Northern province bordering on Colombia), Manabi and Pinchinca (just below Esmeraldas), Los Riós, Guayas (in the centre), and El Oro (in the South on the border with Peru)
  • in the provinces on the Eastern side of the Andes (Amazon region): Sucumbios (in the North), Orellana (Napo river), Pastaza and Morona-Santiago
  • and to a lesser extent in some other provinces: Cotopaxi (central) and Loja (on the border with Peru).

             The recommendations discussed in NOTE 2 apply when staying overnight in primitive conditions below 1500 m.
Recommendation of the WHO concerning yellow fever vaccination: "There is risk of yellow fever in the eastern part of the country. There is no risk in Quito, Guayaquil or the Galapagos Islands.
If you are starting your trip from another country where yellow fever can occur (Africa, South America), vaccination is officially required from the age of 1 year. Citizens and habitants of Ecuador are obliged to be vaccinated against yellow fever when visiting another country where yellow fever can occur (Africa, South-America).

BRITISH GUYANA:

There is no malaria risk in Georgetown and New Amsterdam. There is a quite substantial malaria risk in the rest of the country:

  • highest risk occurs in regions 1(Barimi-Waini), 7 (Cuyuni-Mazaruni), 8 (Potaro-Siparuni), 9 (Upper Takutu-Upper Essequibo) and 10 (Upper Demerara-Berbice);
  • moderate risk in region 2 (Pomeroon-Supenaam) and 3 (Demerara-Mahaica)
  • very low risk in regions 4 (Demerara-Mahaica), 5 (Mahaica-Berbice) and 6 (East Berbice-Corentyne). The recommendations in NOTE 2 apply.
    Recommendation of the WHO concerning yellow fever vaccination: "Vaccination against yellow fever is strongly recommended. Vaccination against yellow fever is anyhow officially required for travellers coming from another country, where yellow fever can occur (Africa, South America - an exception is being made for travellers coming from Trinidad, Tobago, Paraguay, Argentina) or from a country mentioned on http://www.who.int/ith.

FRENCH GUYANA:

There is no malaria risk in Cayenne and Kourou, and the malaria risk is very limited in the rest of the coastal strip. No anti-malaria precautions are necessary.
In the border area with Brazil (different regions along the Oiaopoque river ) and Surinam (different regions along the Maroni river) there is a substantial malaria risk. The guidelines discussed in NOTE 2 apply. In the rest of the country the risk is low to negligible.
Vaccination against yellow fever is obliged for all travellers from the age of 1 year.

PARAGUAY:

In most of Paraguay there is no risk of malaria at all, and therefore no antimalaria precautions are necessary. There is no risk in the towns, nor in the tourist resorts and the surrounding areas, such as the Iguaçu waterfalls.
There is only a limited risk from October to May in some rural areas:

1.       in the West, on the border with Bolivia

2.       in the East on the border with Brazil in the provinces Alto Paraná (towards Foz do Iguaçu), Caaguazu and Canendiyu. The recommendations discussed in NOTE 1 apply for overnight stays in more primitive conditions.
Recommendation of the WHO concerning yellow fever vaccination: "Vaccination against yellow fever is strongly recommended for all travellers from the age of 9 months. If you are starting your trip from another country where yellow fever can occur (Africa, South America), vaccination is officially required from the age of 1 year on."


PERU
:

  • There is no risk of malaria in the large towns (except in the suburbs of Iquitos), nor in areas higher than 2000 m. No preventive antimalaria measures are therefore necessary here.
  • In the coastal areas to the West of the Andes (except for the Northern provinces listed below) the malaria risk is very low to negligible. The precautions against mosquito bites from dusk till dawn are sufficient for travellers staying in primitive conditions in rural areas (in case of fever malaria should always be considered).
  • A risk of malaria exists (including the dangerous Plasmodium falciparum type)

1.       In the Northern provinces in the coastal area on the Pacific Ocean bordering on Ecuador (Tumbes, Piura, Lambayeque) and

2.       in the Amazon region: especially in the provinces Loreto (+ Iquitos), San Martin, Ucayali and the lower provinces of Amazonas (incl. the Chachapoyas area), Cajamarca and Jaen. The recommendations discussed in NOTE 2 apply.

3.       The recommendations in NOTE 1 apply when spending nights under primitive conditions in rural areas in the rest of the country (predominantly the mild P.Vivax), (Madre de Dios province, town of Puerto Maldonado and the lower provinces of La Libertad, Ayacucho, Pasco, Cusco, Huancavelica, Junin and Huànuco). People staying in luxury hotels in the centres of large towns in these regions do not need to take antimalaria tablets but anti-mosquito precautions are just as important here (in case of fever malaria should always be considered).
Recommendation of the WHO concerning yellow fever vaccination: "Vaccination against yellow fever is not obliged, but strongly recommended for travellers visiting the jungle areas below 2300m. Vaccination against yellow fever is NOT necessary for travellers visiting Cuzco and Machu Picchu."

SURINAM:

  • The risk of malaria in Paramaribo and the seven other coastal districts (north of latitude 5° north) is very low to negligible. Malaria tablets do not need to be taken.
  • In the interior there is a great risk of malaria caused by Plasmodium falciparum (in the three Southern districts south of latitude 5° north; beyond the coastal savannah area, with highest risk along the eastern border and in gold mining areas), and the recommendations discussed in NOTE 2 apply.
    Recommendation of the WHO concerning yellow fever vaccination: "Vaccination against yellow fever is strongly recommended.
    If you are starting your trip from another country where yellow fever can occur (Africa, South America), vaccination is officially required from the age of 1 year on.
     

TRINIDAD - TOBAGO:
There is no malaria risk.

Recommendation of the WHO concerning yellow fever vaccination: "Vaccination against yellow fever is strongly recommended for all travellers from the age of 9 months visiting Trinidad; vaccination is not indicated for travellers only visiting Tobago. If you are starting your trip from another country where yellow fever can occur (Africa, South America), vaccination is officially required from the age of 1 year."

VENEZUELA:
Most of the country is malaria-free. There is no malaria risk in the towns. There is no malaria risk on Margarita Island.

  • There is a risk of (falciparum) malaria in a number of low-lying rainforest areas of the states of Amazonas (Alto Orinoco, Atabapo, Atures, Autana, Manapiare, Rio Negro), Anzoàtegui and Bolivar (Caroni, Cedeño, El Callao, Heres, Gran Sabana, Piar, Raul Leoni, Rocio, Sifontes and Sucre) (South of the Orinoco River, on the border with Brazil), Monagas, Sucre and Delta Amacuro (Antonia Diaz, Casacoima, Pedernales; around the delta of the Orinoco). The measures discussed under NOTE 2 could apply here for overnight stays in rainforest areas under adventure-type conditions (incl. for the Angel Falls and Canaima National Park).
  • In a number of rural areas of the states Apure, Monagas, Sucre and Zulia (north of the Orinoco river) there is a limited risk of (especially the) mild vivax malaria. The measures discussed under NOTE 1 apply for overnight stays in primitive, adventure-type conditions.
  • In the remaining provinces there is no risk of malaria at all. This means that malaria tablets need not be taken for most well-organised tourist trips, even to some rainforest areas, and that measures for protection against mosquito bites in the evenings and at night are sufficient here.
    Recommendation of the WHO concerning yellow fever vaccination: "Vaccination against yellow fever is not obliged, but strongly recommended."

 

 

 

 

 

 

PREVENTION OF MALARIA

Precautions against mosquito bites in the evenings and at night are always essential for protection against possible malaria. People visiting endemic malaria areas during the daytime and staying in reputable hotels in the evenings and overnight run no risk, and do not need to take antimalaria tablets. However, they should always have a mosquito repellent with them for application to the skin, in case they cannot get back to the hotel in time in the evening, due for example to problems such as illness, car breakdown etc. They should also generously apply the mosquito repellent to the skin when on a trip or safari in the early morning, in the evening or at night. When on trips of the adventure type out in the countryside, with overnight stays in primitive conditions, it is also advisable to impregnate the mosquito net with permethrine or deltamethrine, a chemical substance that provides an extra mosquito-repellent and mosquitocidal effect, and taking antimalaria tablets is also necessary:
N.B. In many regions in South America ( http://www.dtg.org/21.0.html ) one can dispense with the malaria tablets (also for adventurous travellers) after having an extensive talk with a specialized doctor who will evaluate the malaria risk depending on the type of lodging, and only when strict measures are taken against mosquito bites from dusk till dawn and malaria emergency treatment is available  (Malarone®) with complete instructions.
 

NOTE 1

NIVAQUINE® 3 tablets per week, to be taken all in one dose, starting from 1 week before departure, and continuing until 4 weeks after returning home.

NOTE 2

MALARONE® (1 tablet daily from 1 day before departure until 7 days after returning home) OR DOXYCYCLINE (1 tablet daily from 1 day before departure until 4 weeks after returning home; in some cases a tolerance test during a few days is necessary) OR LARIAM® (1 tablet once a week from 2-3 weeks before departure until 4 weeks after returning home) are the first choice medication.
To get an effective level of LARIAM® in your blood on arrival in the malaria area, it is recommended to start taking this drug 2 to 3 weeks before departure. People who have never taken this medicine should start taking it at least 2 to 3 weeks beforehand to deal with possible side effects (dizziness, insomnia, nightmares, agitation, inexplicable anxiety, cardiac palpitations). Lariam will not be prescribed if the doctor thinks there are contraindications (pregnancy wish, epilepsy, depression, or cardiac rhythm disorders for which medications such as beta-blockers, calcium antagonists of digitalis are being taken), or if you did not tolerate this medication on an earlier occasion. You should continue to take the medication until 4 weeks after returning home. If Lariam® is tolerated well, it can if necessary be taken for many months or even years. For a short trip MALARONE® is an excellent choice. You can also take MALARONE for several months but it is in that case an expensive choice.
DOXYCYCLINE:  100 mg per day, starting the day before departure until 4 weeks after returning home or after leaving risk area. Doxycycline must be taken while sitting down, with plenty of liquid or during a meal. It can sometimes give rise to phototoxicity and fungal infections of the mouth or genitals. Doxycycline can be taken for several months.

All this should be individually discussed with your doctor or with the doctor at a travel advice center.

 

 

 

 

 

 

DIARRHOEA

DIARRHOEA is a frequent problem when travelling. It is not always possible to avoid it, even when traveling in good conditions. Some advice and the correct medications from the travel pharmacy are very useful. Please consult the text on travellers’ diarrhoea, where the measures for prevention and the correct treatment of diarrhoea are discussed.

 

 
DENGUE


In Latin America dengue fever occurs. Prevention = apply protective measures against mosquito bites during the day. Consult the text on dengue - www.travelhealth.be & consult the world card on - www.who.int/ith
® "disease distribution maps".
   

 

 

 

 

 

VACCINATIONS

  • YELLOW FEVER vaccination is necessary (at any rate for visits to certain regions) in Bolivia, Brazil, Colombia, Equador, Guiana (French and British), Peru, Surinam and Venezuela (excl. Isla Margarita) (http://www.who.int/ith/en/index.html - disease distribution maps). It is best to be vaccinated for a visit to any of these countries. If you are starting your trip from another country where yellow fever can occur (Africa, South America), vaccination is officially required, except for a trip to Venezuela, Chile and Argentina. French Guiana always requires a vaccination for all travellers.
  • Going on a trip is furthermore an ideal opportunity to bring TETANUS-, DIPHTHERIA-, PERTUSSIS-, MEASLES and POLIOMYELITIS VACCINATIONS up to date. The American continent has been free of polio for a number of years.
  • Anyone travelling to Latin America, regardless of the duration and the circumstances of the trip, should be vaccinated against HEPATITIS A. Vaccination against TYPHOID is always recommended for people who are travelling in poor hygienic conditions, or who stay abroad frequently or for long periods (e.g. for at least 2-3 weeks), even if in good hygienic conditions. Vaccination against HEPATITIS B is also recommended in a lot of cases. For further details see the general information on VACCINATIONS.
  • People on adventure trips through the countryside lasting more than 4 weeks or people who will be staying there for a long time should consider vaccination against  RABIES.

             All this should be individually discussed with your doctor or with the doctor at a travel advice centre.

 

 

 

CHAGAS DISEASE (OR AMERICAN TRYPANOSOMIASIS)

Hikers travelling through rural areas in Latin America should be aware of the risk of infection caused by a single cell parasite, called Trypanosoma cruzi, and transmitted by large bugs. In these areas, travellers should certainly not stay the night in primitive huts or in open air. If this is unavoidable, and even when staying in cheap hotels, you should always sleep under a mosquito net (and even put a sheet above the net to avoid contact with falling faeces from the triatomes). It is best to use an insect spray if large insects are found in the room (mostly behind picture frames, in drawers or even under the mattress). You should also apply insect repellent to bare skin in the evening.