Trial overview

IMCOVAS

Assessment of the immunogenicity and safety of marketed vaccines for COVID-19 after regular schedule and adapted vaccine schedules and routes: BNT162b2 (Comirnaty®; Pfizer-BioNTech), mRNA-1273 vaccine (COVID-19 vaccine Moderna®; Moderna) and COVID-19 vaccine (ChAdOx1-S [recombinant])(Vaxzevria®, AstraZeneca)
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The IMCOVAS study was a clinical trial investigating eight different vaccination strategies with three COVID-19 vaccines for efficacy and safety:

  • Comirnaty® (Pfizer-BioNTech)

  • Spikevax® (Moderna)

  • Vaxzevria® (AstraZeneca)

The study was sponsored by our academic partner University of Antwerp and funded by the Federal Knowledge Centre for Health Care (KCE).

The study involved 168 healthy people aged between 18 and 55 years. The participants were not allowed to have already experienced COVID-19 infection, nor to have received a COVID-19 vaccine.

The study consisted of seven visits to our study centre and lasted from June 2021 to July 2022.

For more scientific background on the study, please visit the publicly accessible database in which the study is registered.