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Two ITM partner laboratories become new members of WHO's Supranational Reference Laboratory Network

SRL Kigali and SRL Maputo will strengthen the quality and capacity of tuberculosis laboratory services in sub-Saharan Africa.
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On 16 October, the World Health Organization (WHO) announced the appointment of two new members to the WHO Tuberculosis (TB) Supranational Reference Laboratory (SRL) Network: the Rwanda Biomedical Centre National Tuberculosis Reference Laboratory in Kigali, Rwanda (SRL Kigali), and the National Tuberculosis Reference Laboratory in Maputo, Mozambique (SRL Maputo). Thanks to the support of Belgium and Flanders, ITM was able to accompany the preparation work carried out by colleagues in Rwanda and Mozambique. ITM, itself the host of the coordinating WHO TB Supranational Reference Laboratory, Antwerp, is delighted to welcome the new members to the network.

RBC_1x1 Rwanda Biomedical Centre (RBC)

According to the WHO, an estimated 10.7 million people fell ill with tuberculosis (TB) worldwide in 2024, including 1.2 million children. Multidrug-resistant TB continues to be a public health crisis and a threat to global health security. In 2024, only around 40% of people with drug-resistant TB accessed treatment. TB can be fatal without effective treatment.

Because of Rwanda's successes with their strong national TB control programme, WHO has already designated the Rwanda Biomedical Centre (RBC)'s laboratory as a candidate SRL in 2022 to support Francophone African countries, including the Comoros and Madagascar.

The RBC, Rwanda's central health implementation agency under the Ministry of Health, is an ITM partner institute. From 2021 to 2025, the Belgian Ministry of Foreign Affairs, Foreign Trade and Development Cooperation funded a programme to strengthen diagnostic laboratory capacity,  interpretation of diagnostic results, bioinformatics, statistical analysis and surveillance, through technology and knowledge sharing with ITM. Achieving recognised SRL status, which was the main objective of this programme, will enable Rwanda, a country with a medium TB prevalence amidst high-burden countries, to more effectively control drug-resistant tuberculosis also by supporting countries in the region.

ClaudeSemuto_5x4 Jean Claude Semuto Ngabonziza, senior researcher and scientific lead at RBC.

"True capacity building is measured not by workshops or equipment, but by sustainable scientific expertise, strong institutions, and leadership. Rwanda’s recognition as a SRL reflects fifteen years of national commitment, scientific excellence, and strategic partnerships. It formalises our growing role in supporting other countries through laboratory strengthening and scientific capacity building. We sincerely thank the ITM for its longstanding collaboration and invaluable support throughout this journey", Jean Claude Semuto Ngabonziza, Senior Researcher and Scientific Innovation Lead at RBC.

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Between 2013 and 2025, ITM has provided technical support to the Instituto Nacional de Saúde (INS) in Maputo, Mozambique, with focus on institutional capacity strengthening, in the framework of a collaboration with the Flemish Government. In recent years, the cooperation has broadened to include the development of a new comprehensive research strategy, and providing evidence-based policy advice and information for the general public.

Currently, ITM collaborates with INS on research projects, for example, in the framework of the EDCTP-funded Tuberculosis Antimicrobial Stewardship Programme, where INS will carry out reference laboratory work for patients who have a type of tuberculosis that is resistant to all the main drugs.

The INS laboratory's addition to the SRL Network strengthens capacity to provide regional laboratory support, including to Portuguese-speaking countries in Africa.

LeenRigouts_1x1 Leen Rigouts, senior researcher and head of the SRL Laboratory at ITM Antwerp.

Nália Ismael, Head of the Health Technology Development Division at INS says: "Mozambique's designation as a supranational TB reference laboratory is both a recognition of the country's scientific excellence and a commitment to global health. This achievement reflects the dedication and expertise of researchers and technicians, and it strengthens Mozambique's role in providing specialized diagnostic support to other nations particularly for African Portuguese Speaking Countries. By enhancing local capacity for high-quality resistance testing in countries heavily affected by tuberculosis, this milestone accelerates treatment research and contributes to improved patient outcomes. It is a step of national and continental importance, reinforcing Mozambique’s leadership in the fight against TB."

Leen Rigouts, Senior Researcher and Head of the SRL laboratory at ITM Antwerp: "This milestone is the result of the concerted efforts and talents of the researchers in Rwanda and Mozambique. ITM is proud to have accompanied and supported this journey. This increased capacity to conduct high quality resistance testing in countries where TB is still very much present will help advance research on treatments that can benefit patients worldwide, also in Belgium.

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