We chose five talks on various aspects of pathogen transmission for this theme:
These pathogens and transmission aspects are very diverse and specialized. However, each speaker will rather give a bird's-eye view on the topic and emphasize how each particular model provides novel insights and perspectives that will be enlightening and useful for an educated, but not necessarily specialized audience with a broad interest in host-pathogen interactions.
Cross-species transmission of simian retroviruses and new human diseases in Africa
Martine Peeters has a longstanding interest in the origins and evolution of primate lentiviruses.
She was the first to isolate SIVcpz from chimpanzees in Gabon and the DRC. The work on genetic diversity and molecular epidemiology of HIV-1 in Africa, allowed to identify the geographic epicenter and likely point of origin of the HIV-1 group M pandemic.
She documented the extraordinary magnitude of human exposure to simian retroviruses through the hunting and consumption of primate bush meat in Central Africa and identified the chimpanzee reservoirs of HIV-1 group M and N, and SIVs, closely related to HIV-1 group O and P in wild gorillas in Cameroun.
Persistence of pathogens
Martin Eichner graduated as a field biologist, studying the vectors of onchocerciasis in Africa. After that, he moved on to more theoretical work, writing a PhD thesis on the planned global eradication of poliomyelitis.
Having worked in Tübingen (Germany), Kumba (Cameroon), Cambridge (UK), Boston (US) and Helsinki (Finland), he has accumulated over 25 years of experience in mathematical modeling of infectious diseases. His work covers parasitic, bacterial and viral diseases.
He is especially intrigued by the counter-intuitive features which he freuquently encounters in the dynamic systems which describe the transmission and persistence of infectious diseases.
Plasmodium falciparum in South America: Origin and adaptation strategies for survival
Dr. Dionicia Gamboa acquired her expertise in molecular and cellular biology during her PhD at the Institute of Tropical Medicine in Antwerp, Belgium. She specialized on Leishmania parasites.
In 2003 she became the laboratory coordinator of the Malaria Working Group at the Institute of Tropical Medicine Alexander von Humboldt in Lima, Peru. She leads several malaria projects and training courses from basic microscopy to specialized laboratory techniques, aided by the group in charge of the clinical and epidemiological activities in the field.
Dr Gamboa is currently appointed as an assistant professor at the Department of Cellular and Molecular Sciences from the Faculty of Science and Philosophy at the Universidad Peruana Cayetano Heredia in Lima, Peru.
Transmission dynamics and colonization history of schistosomes
Tine Huyse is a FWO postdoctoral researcher working at the ITM and the University of Leuven. Her research interests include transmission strategies and speciation patterns in animal parasites, with an emphasis on African schistosome blood flukes. To this end, molecular data is generated and analyzed using phylogenetic and population genetic analyses. An important aim is to determine the role of parasite genetic variation in schistosomiasis infection and disease development.
Early and outdoor biting malaria vectors: a challenge for malaria elimination
Lies Durnez works at the Medical Entomology Unit of ITM. She has a strong background in reservoir and vector ecology, and molecular biology. Her research, which is field- as well as laboratory-based, mainly focuses on the residual transmission of malaria in South-East Asia, including vector bionomics, research on a possible genetic basis of vector behavior, and innovative vector control measures.